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Endone is a brand name for an opioid pain-relief medicine containing the active ingredient BUY ENDONE 5MG oxycodone. Endone is used to relieve moderate to severe pain – it is not usually recommended for the treatment of chronic (long-term) pain. Endone is only available on prescription from your doctor , BUY ENDONE ONLINE IN AUSTRALIA ENDONE FOR SALE
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This medicine is used to manage moderate to severe pain. BUY ENDONE 5MG
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The active ingredient in this medicine works by binding to receptors called opioid receptors, which are in your central nervous ENDONE FOR SALE system. This binding action changes your body's perception of pain throughout the central nervous system producing the pain relieving (analgesic) effect. BUY ENDONE 5MG
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This medicine is only available with a doctor’s prescription.
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ADDICTION
You can become addicted to ENDONE even if you take it exactly as prescribed. ENDONE may become habit forming causing mental and physical dependence. If abused it may become less able to reduce pain. BUY ENDONE ONLINE IN AUSTRALIA
DEPENDENCE
As with all other opioid containing products, your body may become used to you taking ENDONE. Taking it may result in physical dependence. Physical dependence means that you may experience withdrawal symptoms if you stop taking ENDONE suddenly, so it is important to take it exactly as directed by your doctor.
TOLERANCE
Tolerance to ENDONE may develop, which means that the effect of the medicine may decrease. If this happens, more may be needed to maintain the same effect.
WITHDRAWAL
Continue taking your medicine for as long as your doctor tells you. If you stop taking this medicine suddenly, your pain may worsen and you may experience some or all of the following withdrawal symptoms:
- nervousness, restlessness, agitation, trouble sleeping or anxiety
- body aches, weakness or stomach cramps
- loss of appetite, nausea, vomiting or diarrhoea
- increased heart rate, breathing rate or pupil size
- watery eyes, runny nose, chills or yawning
- increased sweating
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ENDONE given to the mother during labour can cause breathing problems and signs of withdrawal in the newborn.
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When you must not take it
Do not take ENDONE if you have an allergy to:
- any medicine containing oxycodone hydrochloride
- any other narcotic analgesics such as morphine, codeine, or opium
- any of the ingredients listed at the end of this leaflet
Some of the symptoms of an allergic reaction may include:
- shortness of breath
- wheezing or difficulty breathing
- swelling of the face, lips, tongue or other parts of the body
- rash, itching or hives on the skin
Do not take this medicine if you are pregnant. It may affect your developing baby if you take it during pregnancy.
Do not breast-feed if you are taking this medicine. The active ingredient in ENDONE passes into breast milk and there is a possibility that your baby may be affected.
Do not give this medicine to children. Safety and effectiveness in children have not been established. ENDONE FOR SALE
Do not take this medicine if you have or have had any of the following:
- head injury
- brain tumour
- epilepsy or other convulsive disorders
- heart problems such as an irregular and/or rapid heartbeat
- chronic obstructive pulmonary disease, asthma or other respiratory diseases
- severe headaches, or headaches due to raised pressure in the head
- a history of alcohol or drug abuse
- a history of mental illness
Do not take this medicine if you are taking or have taken medicines for depression called Monoamine Oxidase Inhibitors (MAOs) within the last 14 days.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should be taking this medicine, consult your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you currently have or have had any of the following medical conditions:
- muscle weakness
- underactive thyroid
- kidney disease
- liver disease
- low blood pressure
- prostate problems, or difficulty in passing urine
- bowel disorders
If you have not told your doctor about any of the above, tell them before you start taking ENDONE.
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.
Some medicines ENDONE may interfere with each other. These include:
- anaesthetics
- anticoagulants, medicines used to thin the blood
- medicines used to treat epilepsy
- medicines used to help with sleeping
- medicines used to help lower blood pressure
- medicines used to treat anxiety
- medicines used to treat depression
- medicines used to treat “flu” symptoms
- other medicines used to relieve pain
- medicines such as metoclopramides, used to relieve stomach cramps or spasms
- medicines used to treat chronic obstructive pulmonary disorder
These medicines may be affected by ENDONE or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.
How to take ENDONE
Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
How much to take
The usual dose is one tablet every six hours.
Your doctor may prescribe a different dose for you. Be sure to follow your doctor’s directions about when and how to take ENDONE.
How to take it
Swallow the tablets whole with a full glass of water.
When to take it
Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
ENDONE should be taken after food or with milk.
How long to take it
Continue taking your medicine for as long as your doctor tells you.
If you have been using this medicine for a long period of time and it is no longer needed to manage your pain DO NOT stop taking ENDONE suddenly. Your doctor may want you to gradually reduce the amount of ENDONE you are taking before stopping completely in order to lessen the risk of withdrawal symptoms.
If you forget to take it
If it is less than 3 hours before your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints. BUY ENDONE 5MG
If you take too much (overdose)
If you or someone else receives too much (overdose), and experience one or more of the symptoms below, immediately call triple zero (000) for an ambulance. Keep the person awake by talking to them or gently shaking them every now and then. You should follow the above steps even if someone other than you have accidentally used ENDONE that was prescribed for you. If someone takes an overdose, they may experience one or more of the following symptoms: BUY ENDONE 5MG
- slow, unusual or difficult breathing
- drowsiness, dizziness or unconsciousness
- slow or weak heartbeat
- nausea or vomiting
- convulsions or fits
If you think you or someone else may have used too much ENDONE, you should immediately:
- phone the Poisons Information Centre (by calling 13 11 26), or
- contact your doctor, or
- go to the Emergency Department at your nearest hospital.
You should do this even if there are no signs of discomfort or poisoning.
When seeking medical attention, take this leaflet and any remaining medicine with you to show the doctor. Also tell them about any other medicines or alcohol which have been taken. BUY ENDONE 5MG
While you are using ENDONE
Things you must do
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking ENDONE.
Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.
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Keep all of your doctor's appointments so that your progress can be checked.
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It contains the active ingredient oxycodone hydrochloride.
Oxycodone hydrochloride belongs to a class of drugs known as opioid analgesics.
As with all strong painkillers, your body may become used to you taking Oxycodone Sandoz tablets. Taking it may result in physical dependence. Physical dependence means that you may experience withdrawal symptoms if you stop taking Oxycodone Sandoz suddenly, so it is important to take it exactly as directed by your doctor.
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BEFORE YOU TAKE OXYCODONE SANDOZ
Long-term use of oxycodone tablets may result in a decrease in sex hormone levels which may affect sperm production in men and the menstrual cycles in females. Talk to your doctor if you have concerns.
When you must not take it
Do not take this medicine if you have an allergy to:
- oxycodone hydrochloride, or to any of the other ingredients listed at the end of this leaflet under Product Description
- any other similar medicines known as opioid analgesics, e.g. morphine or codeine.
Some of the symptoms of an allergic reaction may include:
- shortness of breath
- wheezing or difficulty breathing
- swelling of the face, lips, tongue or other parts of the body
- rash, itching or hives on the skin.
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Do not take this medicine if you have or have had any of the following medical conditions:
- suffer from shallow breathing or have any breathing problems such as acute asthma, respiratory depression (breathing slows or weakens) or other obstructive airways disease
- severe drowsiness or have a reduced level of consciousness
- irregular or rapid heartbeats or changes in the way the heart beats
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- have swallowing difficulties of narrowing of the oesophagus
- severe liver or kidney disease
- severe depression
- a condition where you have high levels of carbon dioxide in your blood.
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Do not take this medicine if:
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Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
- have sleep apnoea (temporarily stopping breathing while you sleep)
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- severe mental condition involving losing contact with reality, hearing voices or an inability to think clearly
- an addiction or history of abuse of alcohol, opioids or other drugs.
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Pregnancy and breastfeeding
Do not take this medicine if you are pregnant or intend to become pregnant whilst taking this medicine.
It may affect your developing baby if you take it during pregnancy. Like most medicines of this kind, Oxycodone Sandoz tablets are not recommended to be taken during pregnancy. Your doctor will discuss the risks of taking it if you are pregnant.
This medicine is not recommended to be taken during labour.
Oxycodone given to the mother during labour can cause breathing problems in the newborn.
Tell your doctor if you are breastfeeding or plan to breastfeed.
Oxycodone can pass into the breastmilk and can affect the baby. Your doctor can discuss with you the risks and benefits involved.
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Addiction
You can be addicted to Oxycodone Sandoz even if you take it exactly as prescribed. Oxycodone Sandoz may become habit forming causing mental and physical dependence. If abused it may become less able to reduce pain.
Dependence
As with all other opioid containing products, your body may become used to you taking Oxycodone Sandoz. Taking it may result in physical dependence. Physical dependence means that you may experience withdrawal symptoms if you stop taking Oxycodone Sandoz suddenly, so it is important to take it exactly as directed by your doctor.
Tolerance
Tolerance to Oxycodone Sandoz may develop, which means that the effect of the medicine may decrease. If this happens, more may be needed to maintain the same effect.
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Withdrawal
Continue taking your medicine for as long as your doctor tells you. If you stop having this medicine suddenly, your pain may worsen and you may experience some of all of the following symptoms:
- nervousness, restlessness, agitation, trouble sleeping or anxiety
- body aches, weakness or stomach cramps
- loss of appetite, nausea, vomiting or diarrhoea
- increased heart rate, breathing rate or pupil size
- watery eyes, runny nose, chills or yawning
- increased sweating.
Oxycodone Sandoz contains lactose. If you have been told by your doctor that you have intolerance to some sugars, tell your doctor before taking it.
If you have not told your doctor about any of the above, tell him/her before you start taking Oxycodone Sandoz.
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Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.
Some medicines and Oxycodone Sandoz may interfere with each other. These include:
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HOW TO TAKE OXYCODONE SANDOZ
Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions, ask your doctor or pharmacist for help.
How much to take
Your doctor will tell you exactly how much to take.
Follow the instructions given to you by your doctor and pharmacist exactly.
How to take it
Swallow Oxycodone Sandoz tablets whole with a full glass of water or other fluid.
Oxycodone Sandoz tablets should be taken one tablet at a time with enough water to ensure complete swallowing immediately after placing it in the mouth.
Do not pre-soak, lick or wet the tablet before placing in your mouth.
Do not break, chew, crush or dissolve the tablets. This medicine was designed to work properly only if swallowed whole. They may release all their contents at once if broken, chewed, crushed or dissolved, resulting in a risk of overdose or even death.
If you have trouble swallowing your tablets whole, talk to your doctor.
You must only take Oxycodone Sandoz tablets by the mouth. Taking this medicine in a manner other than prescribed by your doctor can be harmful to your health.
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When to take Oxycodone Sandoz
Take this medicine as directed by your doctor.
This medicine should be taken every twelve hours.
Take your tablets at the times you have been told. If, however, you begin to experience pain (breakthrough pain), and you are taking your Oxycodone Sandoz tablets as prescribed, contact your doctor, as your dosage may have to be reviewed.
This medicine must be taken regularly to control the pain. Taking this medicine at regular time intervals means that the onset of pain is prevented. This medicine should not be taken when you feel you need it, as this will cause some pain to be experienced.
Do not take any alcohol while you are being treated with Oxycodone Sandoz.
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How long to take Oxycodone Sandoz
Continue taking your medicine for as long as your doctor recommends.
If you stop taking this medicine suddenly, your pain may worsen and you may experience withdrawal symptoms such as:
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If you forget to take it
If you forget to take a dose, contact your doctor or pharmacist for advice.
Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.
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If you take too much (overdose)
If you or someone else receive too much (overdose), and experience one or more symptoms below, call triple zero (000) for an ambulance. Keep the person awake by talking to them or gently shaking them every now and then. You should follow the steps even if someone other than you have accidentally used Oxycodone Sandoz that was prescribed for you. If someone takes an overdose, they may experience one or more of the following symptoms:
- slow, unusual or difficult breathing
- drowsiness, dizziness or unconsciousness
- slow or weak heartbeat
- nausea or vomiting
- convulsions of fits
If you or someone else may have taken too much Oxycodone Sandoz, you should immediately telephone your doctor or the Poisons Information Centre (telephone Australia 13 11 26 or New Zealand 0800 POISON or 0800 764766) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Oxycodone Sandoz. Do this even if there are no signs of discomfort or poisoning.
When seeking medical attention, take this leaflet and any remaining tablets with you to show the doctor. Also tell them about any other medicines or alcohol which have been taken.
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WHILE YOU ARE TAKING OXYCODONE SANDOZ
Things you must do
Take this medicine exactly as your doctor has prescribed.
Before you start on a new medicine, remind your doctor and pharmacist that you are taking Oxycodone Sandoz.
Visit your doctor regularly for a check-up, and always discuss any problems or difficulties during or after taking this medicine.
Tell your doctor if your pain is getting worse, or if you are having more frequent breakthrough pain.
Tolerance to oxycodone may develop which means that the effect of the medicine may decrease. If this happens, your doctor may review your dose so that you get adequate pain relief.
Keep enough of this medicine with you to last over weekends and holidays.
Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.
If you become pregnant while taking this medicine, tell your doctor immediately.
Things you must not do
Do not give this medicine to anyone else, even if they have the same condition as you.
Do not use this medicine to treat other complaints unless your doctor tells you.
Drinking alcohol whilst taking Oxycodone Sandoz tablets may make you feel more sleepy and increase the risk of serious side effects, such as shallow breathing with the risk of stopping breathing and loss of consciousness.
Do not stop taking this medicine, exceed the dose recommended or change dosage, without checking with your doctor. Over time your body may become used to you taking oxycodone so if you stop taking it suddenly, your pain may worsen and you may have unwanted side effects such as withdrawal symptoms. This is called physical dependence.
If you need to stop taking this medicine, your doctor will gradually reduce the amount you take each day, if possible, before stopping the medicine completely.
This medicine should be taken strictly according to your doctor’s instructions.
Things to be careful of
Do not drive or operate machinery until you know how Oxycodone Sandoz affects you. Oxycodone may cause drowsiness, dizziness, hallucinations, disorientation, blurred vision or other vision problems or may affect alertness. Discuss these aspects and any impact on your driving or operating machinery with your doctor.
Make sure you know how you react to this medicine before you drive a car, operate machinery, or do anything else that could be dangerous if you are drowsy, dizzy or not alert.
You may feel drowsy when you begin to take Oxycodone Sandoz tablets. If you drink alcohol the drowsiness may be worse.
Be careful if you are elderly, unwell or taking other medicines. Some people may experience side effects such as drowsiness, confusion, dizziness and unsteadiness, which may increase the risk of a fall.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. Standing up slowly will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
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Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.[3] It is used to treat anxiety disorders, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting.[3] It is also used during surgery to interfere with memory formation and to sedate those who are being mechanically ventilated.[3][7] It is also used, along with other treatments, for acute coronary syndrome due to cocaine use.[3] It can be given by mouth or as an injection into a BUY ATIVAN LORAZEPAM AUSTRALIA muscle or vein.[3] When given by injection onset of effects is between one and thirty minutes and effects last for up to a day.
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Lorazepam was initially patented in 1963 and went on sale in the United States in 1977.[12][13] It is on the World Health Organization’s List of Essential Medicines.[14] It is available as a generic medication.[3] In 2018, it was the 58th most commonly prescribed medication in the United States, with more than 13 million prescriptions BUY ATIVAN LORAZEPAM AUSTRALIA
Medical uses
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Lorazepam can effectively reduce agitation and induce sleep, and the duration of effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia, especially in the presence of severe anxiety or night terrors. It has a fairly short duration of action. [19]
Withdrawal symptoms, including rebound insomnia and rebound anxiety, may occur after seven days’ use of lorazepam. [20]
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Intravenous diazepam or lorazepam are first-line treatments for convulsive status epilepticus. [21] Lorazepam is more effective than diazepam and intravenous phenytoin in the treatment of status epilepticus and has a lower risk of continuing seizures that might require additional medication. [22] However, phenobarbital has a superior success rate compared to lorazepam and other drugs, at least in the elderly. [23][24]
Lorazepam’s anticonvulsant properties and pharmacokinetic profile make intravenous use reliable for terminating acute seizures, but induce prolonged sedation. Oral benzodiazepines, including lorazepam, are occasionally used as long-term prophylactic treatment of resistant absence seizures; because of gradual tolerance to their anti-seizure effects, benzodiazepines such as lorazepam are not considered first-line therapies. [25]
Lorazepam’s anticonvulsant and CNS depressant properties are useful for the treatment and prevention of alcohol withdrawal syndrome. In this setting, impaired liver function is not a hazard with lorazepam, since lorazepam does not require oxidation, in the liver or otherwise, for its metabolism. [26]BUY ATIVAN LORAZEPAM AUSTRALIA[27]
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Lorazepam is sometimes used for individuals receiving mechanical ventilation. However, in critically ill people, propofol has been found to be superior to lorazepam both in effectiveness and overall cost; as a result, the use of propofol for this indication is now encouraged, whereas the use of lorazepam is discouraged. [28]
Its relative effectiveness in preventing new memory formation, [29] along with its ability to reduce agitation and anxiety, makes lorazepam useful as premedication. It is given before a general anesthetic to reduce the amount of anesthetic required, or before unpleasant awake procedures, such as in dentistry or endoscopies, to reduce anxiety, to increase compliance, and to induce amnesia for the procedure. Lorazepam by mouth is given 90 to 120 minutes before procedures, and intravenous lorazepam as late as 10 minutes before procedures. [30][31][32] Lorazepam is sometimes used as an alternative to midazolam in palliative sedation. [33] In intensive care units lorazepam is sometimes used to produce anxiolysis, hypnosis, and amnesia
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Drowsiness, dizziness, loss of coordination, headache, nausea, blurred vision, change in sexual interest/ability, constipation, heartburn, or change in appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
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Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any unlikely but serious side effects, including: mental/mood changes (such as hallucinations, depression, thoughts of suicide), slurred speech or difficulty talking, vision changes, unusual weakness, trouble walking, memory problems, signs of infection (such as fever, persistent sore throat).
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A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/ tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
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Adults (over 18 years of age)
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Do not exceed the dose recommended by your doctor.
You should check with your doctor or pharmacist if you are not sure.
Swallow your tablets whole with water.
Do not crush, dissolve or chew them.
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Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.[3] It is used to treat anxiety disorders, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting.[3] It is also used during surgery to interfere with memory formation and to sedate those who are being mechanically ventilated.[3][7] It is also used, along with other treatments, for acute coronary syndrome due to cocaine use.[3] It can be given by mouth or as an injection into a muscle or vein.[3] When given by injection onset of effects is between one and thirty minutes and effects last for up buy ativan lorazepam australia to a day.[3]
Common side effects include weakness, sleepiness, low blood pressure, and a decreased effort to breathe.[3] When given intravenously the person should be closely monitored.[3] Among those who are depressed there may be an increased risk of suicide.[3][8] With long-term use, larger doses may be required for the same effect.[3] Physical dependence and psychological dependence may also occur.[3] If stopped suddenly after long-term use, benzodiazepine withdrawal syndrome may occur.[3] Older people more often develop adverse effects.[9] In this age group lorazepam is associated with falls and hip fractures.[10] Due to these concerns, lorazepam use is generally only recommended for up to two to four weeks.[11]
Lorazepam was initially patented in 1963 and went on sale in the United States in 1977.[12][13] It is on the World Health Organization’s List of Essential Medicines.[14] It is available as a generic medication.[3] In 2018, it was the 58th most commonly prescribed medication in the United States, with more than 13 million prescriptions buy ativan lorazepam australia
Medical uses
Anxiety
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Lorazepam is used in the short-term management of severe anxiety. In the US, the FDA advises against use of benzodiazepines such as lorazepam for longer than four weeks. [11][17] It is fast acting, and useful in treating fast onset panic anxiety. [18]
Lorazepam can effectively reduce agitation and induce sleep, and the duration of effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia, especially in the presence of severe anxiety or night terrors. It has a fairly short duration of action. [19]
Withdrawal symptoms, including rebound insomnia and rebound anxiety, may occur after seven days’ use of lorazepam. [20]
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Seizures
Intravenous diazepam or lorazepam are first-line treatments for convulsive status epilepticus. [21] Lorazepam is more effective than diazepam and intravenous phenytoin in the treatment of status epilepticus and has a lower risk of continuing seizures that might require additional medication. [22] However, phenobarbital has a superior success rate compared to lorazepam and other drugs, at least in the elderly. [23][24]
Lorazepam’s anticonvulsant properties and pharmacokinetic profile make intravenous use reliable for terminating acute seizures, but induce prolonged sedation. Oral benzodiazepines, including lorazepam, are occasionally used as long-term prophylactic treatment of resistant absence seizures; because of gradual tolerance to their anti-seizure effects, benzodiazepines such as lorazepam are not considered first-line therapies. [25]
Lorazepam’s anticonvulsant and CNS depressant properties are useful for the treatment and prevention of alcohol withdrawal syndrome. In this setting, impaired liver function is not a hazard with lorazepam, since lorazepam does not require oxidation, in the liver or otherwise, for its metabolism. [26][27]
Sedation
Lorazepam is sometimes used for individuals receiving mechanical ventilation. However, in critically ill people, propofol has been found to be superior to lorazepam both in effectiveness and overall cost; as a result, the use of propofol for this indication is now encouraged, whereas the use of lorazepam is discouraged. [28]
Its relative effectiveness in preventing new memory formation, [29] along with its ability to reduce agitation and anxiety, makes lorazepam useful as premedication. It is given before a general anesthetic to reduce the amount of anesthetic required, or before unpleasant awake procedures, such as in dentistry or endoscopies, to reduce anxiety, to increase compliance, and to induce amnesia for the procedure. Lorazepam by mouth is given 90 to 120 minutes before procedures, and intravenous lorazepam as late as 10 minutes before procedures. [30][31][32] Lorazepam is sometimes used as an alternative to midazolam in palliative sedation. [33] In intensive care units lorazepam is sometimes used to produce anxiolysis, hypnosis, and amnesia
Results
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Drowsiness, dizziness, loss of coordination, headache, nausea, blurred vision, change in sexual interest/ability, constipation, heartburn, or change in appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
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Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any unlikely but serious side effects, including: mental/mood changes (such as hallucinations, depression, thoughts of suicide), slurred speech or difficulty talking, vision changes, unusual weakness, trouble walking, memory problems, signs of infection (such as fever, persistent sore throat).
Get medical help right away if you have any rare but very serious side effects, including: yellowing eyes or skin, seizures, slow/shallow breathing.
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A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/ tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US –
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Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health
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